Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

Abstract Background Several inhaled drugs are dependent on organic cation transporters to cross cell membranes. To further evaluate their potential to impact on inhaled drug disposition, the localization of MATE1, P-gp, OCTN1 and OCTN2 were investigated in human lung. Methods Transporter proteins we...

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Autors principals:	Tove Berg, Tove Hegelund-Myrbäck, Johan Öckinger, Xiao-Hong Zhou, Marie Brännström, Michael Hagemann-Jensen, Viktoria Werkström, Janeric Seidegård, Johan Grunewald, Magnus Nord, Lena Gustavsson
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-04-01
Col·lecció:	Respiratory Research
Matèries:	MATE1 P-gp OCTN1 OCTN2 Immunohistochemistry COPD
Accés en línia:	http://link.springer.com/article/10.1186/s12931-018-0760-9
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