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Evaluation of in-house PCR for diagnosis of smear-negative pulmonary tuberculosis in Kampala, Uganda

<p>Abstract</p> <p>Background</p> <p>Nucleic acid amplification tests (NAATs) have offered hope for rapid diagnosis of tuberculosis (TB). However, their efficiency with smear-negative samples has not been widely studied in low income settings. Here, we evaluated in-house PCR assay for diagnosis of s...

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Principais autores: Nakiyingi Lydia, Kateete David P, Ocama Ponsiano, Worodria William, Sempa Joseph B, Asiimwe Benon B, Katabazi Fred A, Katamba Achilles, Huang Laurence, Joloba Moses L, Mayanja-Kizza Harriet
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-09-01
Serier:BMC Research Notes
Fag:
Pulmonary tuberculosis
Smear-negative TB
HIV-infected
HIV-TB co-infection
CD4 cell counts
Nucleic acid amplification tests
In-house PCR
Lowenstein-Jensen culture
Sensitivity
Specificity
Resource limited settings
Online adgang:http://www.biomedcentral.com/1756-0500/5/487
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