SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining

Abstract Background DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mamma...

Descrición completa

Detalles Bibliográficos

Principais autores:	Meghana Manjunath, Bibha Choudhary, Sathees C. Raghavan
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2021-06-01
Series:	Cancer Reports
Assuntos:	chemotherapy DNA double‐strand break DNA repair inhibitors genome editing homologous recombination nonhomologous DNA end‐joining
Acceso en liña:	https://doi.org/10.1002/cnr2.1341
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!