Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells

Dendritic cells (DC) initiate the differentiation of CD4+ helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis. In mice, Th1 and Th17 responses are regulated by different conventional (c) DC subsets, with...

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Hlavní autoři:	Ingrid M. Leal Rojas, Wai-Hong Mok, Frances E. Pearson, Yoshihito Minoda, Tony J. Kenna, Ross T. Barnard, Kristen J. Radford
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2017-08-01
Edice:	Frontiers in Immunology
Témata:	dendritic cell CD141+ dendritic cells CD1c+ dendritic cells Th1 Th17 memory CD4+ T cells
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00971/full
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