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STING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells

Abstract Antigen-specific T cell receptor-engineered T cell (TCR-T) based immunotherapy has proven to be an effective method to combat cancer. In recent years, cross-talk between the innate and adaptive immune systems may be requisite to optimize sustained antigen-specific immunity, and the stimulat...

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Autori principali: Ling Wang, Zhaoduan Liang, Yunzhuo Guo, Jean de Dieu Habimana, Yuefei Ren, Obed Boadi Amissah, Omar Mukama, Siqi Peng, Xuanyan Ding, Linshuang Lv, Junyi Li, Min Chen, Zhaoming Liu, Rongqi Huang, Yinchao Zhang, Yi Li, Zhiyuan Li, Yirong Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-04-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-024-06638-1
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