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Investigating the effect of Arvcf reveals an essential role on regulating the mesolimbic dopamine signaling-mediated nicotine reward

Abstract The mesolimbic dopamine system is crucial for drug reinforcement and reward learning, leading to addiction. We previously demonstrated that Arvcf was associated significantly with nicotine and alcohol addiction through genome-wide association studies. However, the role and mechanisms of Arv...

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Hlavní autoři: Yan Wang, Zhongli Yang, Xiaoqiang Shi, Haijun Han, Andria N. Li, Bin Zhang, Wenji Yuan, Yan-Hui Sun, Xiao-Ming Li, Hong Lian, Ming D. Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-03-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-025-07837-y
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