The podocyte-specific knockout of palladin in mice with a 129 genetic background affects podocyte morphology and the expression of palladin interacting proteins
Proper and size selective blood filtration in the kidney depends on an intact morphology of podocyte foot processes. Effacement of interdigitating podocyte foot processes in the glomeruli causes a leaky filtration barrier resulting in proteinuria followed by the development of chronic kidney disease...
Sparad:
| Huvudupphov: | , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Public Library of Science (PLoS)
2021-01-01
|
| Serie: | PLoS ONE |
| Länkar: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654177/?tool=EBI |
| Taggar: |
Inga taggar, Lägg till första taggen!
|