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Repeated Ethanol Exposure Alters DNA Methylation Status and Dynorphin/Kappa-Opioid Receptor Expression in Nucleus Accumbens of Alcohol-Preferring AA Rats

Growing evidence suggests that epigenetic mechanisms, such as DNA methylation and demethylation, and histone modifications, are involved in the development of alcohol and drug addiction. However, studies of alcohol use disorder (AUD) that are focused on epigenetic DNA modifications and gene expressi...

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Hlavní autoři: Kerly Niinep, Kaili Anier, Tony Eteläinen, Petteri Piepponen, Anti Kalda
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-11-01
Edice:Frontiers in Genetics
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2021.750142/full
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