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Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family

Abstract Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical protein, BPSL1038, is conserved across seven bacterial genera and 654 Burkholderia spp. Here, we present a 1.55 Å resolution crystal structure of...

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Bibliográfalaš dieđut
Váldodahkkit: Sofiyah Shaibullah, Nurshahirah Shuhaimi, De-Sheng Ker, Nurhikmah Mohd-Sharif, Kok Lian Ho, Aik-Hong Teh, Jitka Waterman, Thean-Hock Tang, Rui-Rui Wong, Sheila Nathan, Rahmah Mohamed, Min Jia Ng, Shin-Yee Fung, Mohd Anuar Jonet, Mohd Firdaus-Raih, Chyan Leong Ng
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2023-09-01
Ráidu:Communications Biology
Liŋkkat:https://doi.org/10.1038/s42003-023-05265-4
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