Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development

\Levels of progesterone, an endogenous female hormone, increase after ovulation; progesterone is crucial in the luteal phase to maintain successful pregnancy and prevent early miscarriage. Both endogenous and exogenous progesterone are recycled between the liver and gut; thus, the gut microbiota reg...

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Detalhes bibliográficos

Principais autores:	Mei-Jou Chen, Chia-Hung Chou, Tsun-Hsien Hsiao, Tien-Yu Wu, Chi-Ying Li, Yi-Lung Chen, Kuang-Han Chao, Tzong-Huei Lee, Ronnie G. Gicana, Chao-Jen Shih, Guo-Jie Brandon-Mong, Yi-Li Lai, Po-Ting Li, Yu-Lin Tseng, Po-Hsiang Wang, Yin-Ru Chiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2024-12-01
coleção:	Gut Microbes
Assuntos:	Clostridium innocuum epipregnanolone gut microbiome infertility low progesterone bioavailability mouse
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/19490976.2024.2424911
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