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Identifying plant-derived antiviral alkaloids as dual inhibitors of SARS-CoV-2 main protease and spike glycoprotein through computational screening

COVID-19 is currently considered the ninth-deadliest pandemic, spreading through direct or indirect contact with infected individuals. It has imposed a consistent strain on both the financial and healthcare resources of many countries. To address this challenge, there is a pressing need for the deve...

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Glavni autori: Ramsha Yamin, Iqra Ahmad, Hira Khalid, Asia Perveen, Sumra Wajid Abbasi, Umar Nishan, Sheheryar Sheheryar, Arlindo Alencar Moura, Sarfraz Ahmed, Riaz Ullah, Essam A. Ali, Mohibullah Shah, Suvash Chandra Ojha
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2024-07-01
Serija:Frontiers in Pharmacology
Teme:
alkaloids
main protease
spike glycoprotein
secondary metabolites
SARS-CoV-2
Online pristup:https://www.frontiersin.org/articles/10.3389/fphar.2024.1369659/full
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