Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake.

Maximal oxygen uptake (VO(2max)) predicts mortality and is associated with endurance performance. Trained subjects have a high VO(2max) due to a high cardiac output and high metabolic capacity of skeletal muscles. Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a nuclear recept...

Descripción completa

Detalles Bibliográficos

Autores principales:	Miki Tadaishi, Shinji Miura, Yuko Kai, Yutaka Kano, Yuichi Oishi, Osamu Ezaki
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2011-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3234261?pdf=render
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!