Antinuclear antibodies produced in HLA-DR transgenic humanized mice developed chronic graft-versus-host disease

Background: Chronic graft versus host disease (GVHD) has been reported in humanized mice after the implantation of human hematopoietic stem cells (hu-HSC). As such, humanized mice have been applied to a mouse model of chronic GVHD; however, B-cell activation and autoantibody production did not occur...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Hiroshi Tsuzuki, Yasuko Nagatsuka, Mitsuhiro Iwata, Noboru Kitamura, Yosuke Nagasawa, Taro Matsumoto, Ryoji Ito, Takeshi Takahashi, Mamoru Ito, Hideki Nakamura, Masami Takei
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2021-11-01
Цуврал:	Heliyon
Нөхцлүүд:	Chronic GVHD HLA-DR transgenic humanized mouse Autoantibody Antinuclear antibody
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S240584402102483X
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!