The CoolCot trial: active methods of therapeutic hypothermia for newborns with hypoxic ischaemic encephalopathy (HIE) during neonatal transport: a study protocol for a randomised controlled trial comparing battery-enabled servo-controlled cooling blankets and ice-gel pack methods

Abstract Background Impaired oxygen delivery or blood flow to the brain around the time of birth can cause injury. Hypoxic ischaemic encephalopathy (HIE) is a leading cause of death and disability in term and near-term infants. Therapeutic hypothermia (TH) (reducing body temperature to 33–34 °C for...

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Hauptverfasser:	Adam Heathcote, Kate Hooper, Matt Cooper, Sebastian Lee, Fan Tang, Vamsi Batta, Saumil Desai, Jacqueline Gardiner, Alex Wilson, Kylie McDonald, Alysha Timoney, Tess Watson, Jonathan Davis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-09-01
Schriftenreihe:	Trials
Schlagworte:	Hypoxic ischaemic encephalopathy Therapeutic hypothermia Servo-controlled cooling Neonatal transport Randomised control trial
Online-Zugang:	https://doi.org/10.1186/s13063-025-09111-2
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