Dimethyl Fumarate Reverses β‐Adrenoceptor–Mediated Myocardial Fibrosis in Mice by Inhibiting Yes‐Associated Protein–Regulated Expression of Intermediate‐Conductance Ca2+‐Activated K+ Channel in Fibroblasts

Background Myocardial fibrosis is a pivotal pathological component of the failing heart where the sympatho‐β‐adrenergic receptor (β‐AR) signaling is augmented. Intermediate‐conductance Ca2+‐activated K+ channel (KCa3.1) is expressed in fibroblasts and mediates fibrosis, but the regulation of KCa3.1...

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Үндсэн зохиолчид:	Lin‐Hong Wu, Ru‐Yue Bai, Jia‐Yi Chen, Zheng‐Da Pang, Xia‐Xia Hai, Meng‐Zhuan Han, Yi‐Yi Yang, Yan Wang, Yi Zhang, Jie Zhang, Gang She, Xiao‐Jun Du, Xiu‐Ling Deng
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2026-04-01
Цуврал:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Нөхцлүүд:	dimethyl fumarate KCa3.1 channel myocardial fibrosis YAP β‐adrenergic receptor
Онлайн хандалт:	https://www.ahajournals.org/doi/10.1161/JAHA.125.046565
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!