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Escape From Cisplatin-Induced Senescence of Hypoxic Lung Cancer Cells Can Be Overcome by Hydroxychloroquine

Chemotherapy is the commonly used treatment for advanced lung cancer. However, it produces side effects such as the development of chemoresistance. A possible responsible mechanism may be therapy-induced senescence (TIS). TIS cells display increased senescence-associated β-galactosidase (SA-β-gal) a...

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Principais autores: Aleksandra Olszewska, Agata Borkowska, Monika Granica, Justyna Karolczak, Bartosz Zglinicki, Claudine Kieda, Halina Was
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2021.738385/full
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