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Electrophilic aryl spiroannulation induced by diaryliodonium salts: efficient synthesis of [5,5]-spiro lactone-lactam scaffolds from α-cyanocarboxylates

Spirocyclic architectures represent one of the privileged three-dimensional scaffolds in pharmaceutical chemistry and drug discovery, while the new-skeletal synthesis of spiromolecules from simple starting materials remains a challenging task. Here, we report the first diaryliodonium salt-mediated e...

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Bibliografiske detaljer
Principais autores: Zhiyuan Bao, Yifei Li, Ruitong Zhang, Zhengsen Yu, Chao Chen
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co. Ltd. 2026-06-01
Serier:Green Synthesis and Catalysis
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2666554924000644
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