Puerarin ameliorates high glucose-induced MIN6 cell injury by activating PINK1/Parkin-mediated mitochondrial autophagy

The dysfunction of pancreatic β-cells plays a pivotal role in the pathogenesis of type 2 diabetes mellitus (T2DM). Despite numerous studies demonstrating the anti-inflammatory and antioxidant properties of puerarin, the protective effects of puerarin on β-cells remain poorly understood. Hence, this...

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Detalhes bibliográficos

Principais autores:	Hongyang Zhu, You Yu, Yuting Li, Shiyao Chang, Yuhui Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Heliyon
Assuntos:	Type 2 diabetes β-cell dysfunction Puerarin Mitochondrial autophagy Mitochondrial apoptosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024122074
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