A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling

Summary: A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood. Here, we show that the offspring of high-fat diet (HFD)-fed mother...

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Autori principali:	Bodie Curren, Tufael Ahmed, Ridwan B. Rashid, Ismail Sebina, Md. Al Amin Sikder, Daniel R. Howard, Mariah Alorro, Md. Ashik Ullah, Alec Bissell, Muhammed Mahfuzur Rahman, Michael A. Pearen, Grant A. Ramm, Antiopi Varelias, Stefan Rose-John, Kelli P.A. MacDonald, Robert Hoelzle, Páraic Ó Cuív, Kirsten M. Spann, Paul G. Dennis, Simon Phipps
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-11-01
Serie:	Cell Reports
Soggetti:	CP: Immunology CP: Metabolism
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124724013251
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