Chondrogenic differentiation of human bone marrow MSCs in osteochondral implants under kinematic mechanical load is dependent on the underlying osteo component

Chondrogenic models utilizing human mesenchymal stromal cells (hMSCs) are often simplistic, with a single cell type and the absence of mechanical stimulation. Considering the articulating joint as an organ it would be beneficial to include more complex stimulation. Within this study we applied clini...

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Bibliografski detalji

Glavni autori:	Graziana Monaco, Feras Qawasmi, Alicia J. El Haj, Nicolas R. Forsyth, Martin J. Stoddart
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-10-01
Serija:	Frontiers in Bioengineering and Biotechnology
Teme:	osteochondral chondrogenesis crosstalk tissue engineering scaffold signalling
Online pristup:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.998774/full
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