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A simple PCR-RFLP method for genetic phase determination in compound heterozygotes

When susceptibility to diseases is caused by cis-effects of multiple alleles at adjacent polymorphic sites, it may be difficult to assess with confidence the genetic phase and identify individuals carrying the risk haplotype. Experimental assessment of genetic phase is still challenging and most po...

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Bibliografski detalji
Glavni autori: Rodney T Perry, Harsh eDwivedi, Brahim eAissani
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2012-01-01
Serija:Frontiers in Genetics
Teme:
Online pristup:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00108/full
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