Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites.

Invasion by the malaria merozoite depends on recognition of specific erythrocyte surface receptors by parasite ligands. Plasmodium falciparum uses multiple ligands, including at least two gene families, reticulocyte binding protein homologues (RBLs) and erythrocyte binding proteins/ligands (EBLs). T...

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Detalhes bibliográficos

Principais autores:	Xiaohong Gao, Kim Pin Yeo, Siqi Sharon Aw, Claudia Kuss, Jayasree K Iyer, Saraswathy Genesan, Ravikumar Rajamanonmani, Julien Lescar, Zbynek Bozdech, Peter R Preiser
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2008-07-01
coleção:	PLoS Pathogens
Acesso em linha:	http://europepmc.org/articles/PMC2438614?pdf=render
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