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BRD4 Inhibitor Alleviates Recurrent Spontaneous Abortion via Regulating BRD4/STAT3/IL‐17A Axis to Decrease the Th17 Cell Differentiation

ABSTRACT Purpose Recurrent spontaneous abortion (RSA) is an abnormal phenomenon that severely affects women's quality of life. Inhibiting Th17 cell differentiation can alleviate RSA. This research explored the mechanism by which BRD4 Inhibitor (BETi) suppressed the differentiation of Th17 cells to m...

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Principais autores: Fen Liu, Zhenhui Zhang, Chengying Yang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-01-01
Serier:Reproductive Medicine and Biology
Fag:
BETi
BRD4
IL‐17A
recurrent spontaneous abortion
STAT3
Th17 cell differentiation
Online adgang:https://doi.org/10.1002/rmb2.12682
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