Development of an over-gap droplet digital PCR assay and evaluation of serum HBcrAg/qAnti-HBc as noninvasive markers for intrahepatic replication-competent HBV DNA in chronic hepatitis B patients with HBsAg loss

This study assessed serum hepatitis B core-related antigen (HBcrAg) and antibodies to hepatitis B core antigen (qAnti-HBc) as noninvasive biomarkers for detecting intrahepatic replication-competent HBV DNA (repDNA) in chronic hepatitis B (CHB) patients who had lost HBsAg. The goal was to identify al...

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Hauptverfasser:	Guangxin Yu, Yan Liu, He Zhang, Mingwei Li, Le Li, Bei Jiang, Dandan Liang, Xiaoyong Li, Minggui Lin, Hongxing Han, Jiuxin Qu, Fengmin Lu, Hao Liao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2025-12-01
Schriftenreihe:	Emerging Microbes and Infections
Schlagworte:	Replication-competent HBV DNA HBV core-related antigen anti-HBc functional cure HBsAg loss
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/22221751.2025.2589548
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