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Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity

Resistance to chemotherapy-induced cell death represents a major obstacle in the treatment of acute myeloid leukemia. APRIL (A Proliferation Inducing Ligand) is a member of the tumor necrosis factor superfamily that plays a key role in normal B-cell development, while promoting survival and prolifer...

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Bibliografische Detailangaben
Hauptverfasser: Désirée Bonci, Maria Musumeci, Valeria Coppola, Antonio Addario, Concetta Conticello, Michael Hahne, Massimo Gulisano, Francesco Grignani, Ruggero De Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2008-12-01
Schriftenreihe:Haematologica
Online-Zugang:https://haematologica.org/article/view/5116
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