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Transient Exposure of Tissue-Engineered Cartilage Analogs to Synovial Fluid Hematoma After Ankle Fracture Promotes Chondrocyte Death and Alters Gene Expression Toward an Osteoarthritic Phenotype

Category: Basic Sciences/Biologics; Ankle Arthritis Introduction/Purpose: The first stage of fracture healing consists of hematoma formation with recruitment of proinflammatory cytokines and matrix metalloproteinases. Unfortunately, when there is an intra-articular fracture, these inflammatory media...

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Principais autores: Nicholas Allen, Alexandra Hunter Aitchison BS, Kian Bagheri BA, Nicholas Guardino BS, Bijan Abar BS MHS, Albert T. Anastasio MD, Samuel Adams MD
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2023-12-01
Serier:Foot & Ankle Orthopaedics
Online adgang:https://doi.org/10.1177/2473011423S00212
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