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The molecular subtypes of triple negative breast cancer were defined and a ligand-receptor pair score model was constructed by comprehensive analysis of ligand-receptor pairs

BackgroundIntercellular communication mediated by ligand-receptor interactions in tumor microenvironment (TME) has a profound impact on tumor progression. This study aimed to explore the molecular subtypes mediated by ligand-receptor (LR) pairs in triple negative breast cancer (TNBC), identify the m...

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Principais autores: Weijun Pan, Kai Song, Yunli Zhang, Ciqiu Yang, Yi Zhang, Fei Ji, Junsheng Zhang, Jian Shi, Kun Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
coleção:Frontiers in Immunology
Assuntos:
triple negative breast cancer
ligand-receptor pairs
tumor microenvironment
drug susceptibility
immunotherapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.982486/full
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