A convenient method for the construction of triazole-bonded chalcone derivatives from acetophenone: Synthesis and free radical scavenging investigation

The substituted 1,2,3-triazole core is prevalent in numerous commercially available drugs utilized for a wide range of clinical applications. Simultaneously, chalcone represents a privileged framework discovered in natural products exhibiting intriguing bioactivities. In this study, we synthesized t...

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Hauptverfasser:	Atta Ullah, Nur Rohman, Bayu Ardiansah, Antonius Herry Cahyana, Abdulrahman A. Almehizia
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-12-01
Schriftenreihe:	MethodsX
Schlagworte:	Synthesis of triazole-bonded chalcone derivatives via three steps reaction: aldol condensation, propargylation, and then copper-mediated azide-alkyne cyclization
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2215016123003199
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