Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis

ABSTRACT Aspergillus fumigatus is a devastating opportunistic fungal pathogen causing hundreds of thousands of deaths every year. Phosphoglucose isomerase (PGI) is a glycolytic enzyme that converts glucose-6-phosphate to fructose-6-phosphate, a key precursor of fungal cell wall biosynthesis. Here, w...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Yao Zhou, Kaizhou Yan, Qijian Qin, Olawale G. Raimi, Chao Du, Bin Wang, Chukwuemeka Samson Ahamefule, Bartosz Kowalski, Cheng Jin, Daan M. F. van Aalten, Wenxia Fang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology 2022-08-01
श्रृंखला:	mBio
विषय:	fungi Aspergillus fumigatus carbon flux cell wall drug target phosphoglucose isomerase
ऑनलाइन पहुंच:	https://journals.asm.org/doi/10.1128/mbio.01426-22
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