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Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

Background. The leading cause of mortality in patients with Marfan syndrome (MFS) is thoracic aortic aneurysm and dissection. Notch signaling is essential for vessel morphogenesis and function. However, the role of Notch signaling in aortic pathology and aortic smooth muscle cell (SMC) differentiati...

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主要な著者: Kathryn Jespersen, Chenxin Li, Rishi Batra, Christopher A. Stephenson, Paul Harding, Kylie Sestak, Ryan T. Foley, Harrison Greene, Trevor Meisinger, Jason R. Cook, B. Timothy Baxter, Wanfen Xiong
フォーマット: Artigo
言語:Inglês
出版事項: Wiley 2022-01-01
シリーズ:Journal of Immunology Research
オンライン・アクセス:http://dx.doi.org/10.1155/2022/7538649
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