Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR

Abstract Group B Streptococcus (GBS) remains the most common Gram‐positive bacterium causing neonatal meningitis and GBS meningitis continues to be an important cause of mortality and morbidity. In this study, we showed that GBS penetration into the brain occurred initially in the meningeal and cort...

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Principais autores:	Ningyu Zhu, Chengxian Zhang, Atish Prakash, Zheng Hou, Wei Liu, Weifeng She, Andrew Morris, Kwang Sik Kim
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer Nature 2021-01-01
Series:	EMBO Molecular Medicine
Assuntos:	blood–brain barrier CysLTs EGFR GBS meningitis S1P
Acceso en liña:	https://doi.org/10.15252/emmm.202012651
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