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Human adipose-derived stem cells enriched with VEGF-modified mRNA promote angiogenesis and long-term graft survival in a fat graft transplantation model

Abstract Background Fat grafting, as a standard treatment for numerous soft tissue defects, remains unpredictable and technique-dependent. Human adipose-derived stem cells (hADSCs) are promising candidates for cell-assisted therapy to improve graft survival. As free-living fat requires nutritional a...

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Principais autores: Fei Yu, Nevin Witman, Dan Yan, Siyi Zhang, Meng Zhou, Yan Yan, Qinke Yao, Feixue Ding, Bingqian Yan, Huijing Wang, Wei Fu, Yang Lu, Yao Fu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-11-01
coleção:Stem Cell Research & Therapy
Assuntos:
hADSCs
modVEGF
Fat transplantation
Angiogenesis
Graft survival
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-02008-8
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