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Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas

Introduction: Ferroptosis is a new mode of programmed cell death distinct from necrosis, apoptosis, and autophagy, induced by iron-ion-dependent lipid peroxide accumulation. Circular RNAs are a class of endogenous non-coding RNAs that regulate the biological behavior of tumors. However, the role of...

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Hauptverfasser: Kai Sun, Ling Gao, Shaoming Li, Jingjing Zheng, Zhuang Zhu, Keqian Zhi, Wenhao Ren
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-08-01
Schriftenreihe:Frontiers in Pharmacology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1432520/full
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