Targeting DEC-205−DCIR2+ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis

Abstract Background Dendritic cells (DC) induce adaptive responses against foreign antigens, and play an essential role in maintaining peripheral tolerance to self-antigens. Therefore they are involved in preventing fatal autoimmunity. Selective delivery of antigens to immature DC via the endocytic...

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Hlavní autoři:	Inna Tabansky, Derin B. Keskin, Deepika Watts, Cathleen Petzold, Michael Funaro, Warren Sands, Paul Wright, Edmond J. Yunis, Souhel Najjar, Betty Diamond, Yonghao Cao, David Mooney, Karsten Kretschmer, Joel N. H. Stern
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-05-01
Edice:	Molecular Medicine
Témata:	Multiple sclerosis DCIR2 Regulatory T cells PLP139–151 T cells Dendritic cells
On-line přístup:	http://link.springer.com/article/10.1186/s10020-018-0017-6
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