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Human corneal limbal organoids maintaining limbal stem cell niche function

Corneal epithelial stem cells reside in the limbal area between the cornea and conjunctiva. We examined the potential use of limbal organoids as a source of transplantable limbal stem cells. After treating tissue with collagenase, limbal cells were seeded onto Matrigel and cultivated using limbal ph...

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Bibliografische Detailangaben
Hauptverfasser: Kazunari Higa, Junko Higuchi, Reona Kimoto, Hideyuki Miyashita, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020-12-01
Schriftenreihe:Stem Cell Research
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S1873506120303135
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