Role of ACTH in the interactive/paracrine regulation of adrenal steroid secretion in physiological and pathophysiological conditions

In the normal human adrenal gland, steroid secretion is regulated by a complex network of autocrine/paracrine interactions involving bioactive signals released by endothelial cells, nerve terminals, chromaffin cells, immunocompetent cells and adrenocortical cells themselves. ACTH can be locally prod...

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Autori principali:	Herve Lefebvre, Michael Thomas, Céline DUPARC, Jerome Bertherat, Estelle Louiset
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2016-07-01
Serie:	Frontiers in Endocrinology
Soggetti:	Hyperplasia ACTH VEGF endothelial cell biology cortisol levels Cushing’s syndrome
Accesso online:	http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00098/full
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