Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia

Abstract Primary cilia are sensory organelles that regulate various signaling pathways. When microtubules are compared to a highway, motor proteins carry and transport cargo proteins, which are tuned by post-translational modifications, such as acetylation. However, the role of acetylation in primar...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jae Hee Jun, Hwayeon Cha, Je Yeong Ko, Ho-Shik Kim, Kyung Hyun Yoo, Jong Hoon Park
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-01-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Acetylation Ciliogenesis Intraflagellar transport Kat2b Primary cilia
Онлайн хандалт:	https://doi.org/10.1038/s41598-025-86292-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!