Quantification of galactosylsphingosine in the twitcher mouse using electrospray ionization-tandem mass spectrometry

Globoid cell leukodystrophy (Krabbe disease) is an autosomal recessive inherited neurodegenerative disorder caused by the deficiency of the lysosomal enzyme β-galactosylceramidase. The pathogenesis of the disorder has been proposed to arise from the accumulation of the cytotoxic metabolite galactosy...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Phillip D. Whitfield, Peter C. Sharp, Rosanne Taylor, Peter Meikle
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2001-12-01
Edice:	Journal of Lipid Research
Témata:	globoid cell leukodystrophy Krabbe disease lysoglycosphingolipids psychosine solid-phase extraction
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S002222752031539X
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!