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A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide.

Formaldehyde (FA) induces neurotoxicity by overproduction of intracellular reactive oxygen species (ROS). Increasing studies have shown that hydrogen sulfide (H(2)S), an endogenous gastransmitter, protects nerve cells against oxidative stress by its antioxidant effect. It has been shown that overpro...

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Principais autores: Xiao-Qing Tang, Heng-Rong Fang, Cheng-Fang Zhou, Yuan-Yuan Zhuang, Ping Zhang, Hong-Feng Gu, Bi Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3554621?pdf=render
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