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TRAF7 determines circadian period through ubiquitination and degradation of DBP

Abstract D-site binding protein, DBP, is a clock-controlled transcription factor and drives daily rhythms of physiological processes through the regulation of an array of genes harboring a DNA binding motif, D-box. DBP protein levels show a circadian oscillation with an extremely robust peak/trough...

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Bibliografische Detailangaben
Hauptverfasser: Shusaku Masuda, Nobuhiro Kurabayashi, Rina Nunokawa, Yuta Otobe, Hiroko Kozuka-Hata, Masaaki Oyama, Yuri Shibata, Jun-ichiro Inoue, Michinori Koebis, Atsu Aiba, Hikari Yoshitane, Yoshitaka Fukada
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-10-01
Schriftenreihe:Communications Biology
Online-Zugang:https://doi.org/10.1038/s42003-024-07002-x
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