Local and Systemic CD4+ T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis

Investigation of the Th1 immune response in sarcoidosis CD4+ T cells has revealed reduced proliferative capacity and cytokine expression upon TCR stimulation. In other disease models, such cellular dysfunction has been associated with a step-wise, progressive loss of T cell function that results fro...

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Autores principales:	Charlene Hawkins, Guzel Shaginurova, D. Auriel Shelton, Jose D. Herazo-Maya, Kyra A. Oswald-Richter, Joseph E. Rotsinger, Anjuli Young, Lindsay J. Celada, Naftali Kaminski, Carla Sevin, Wonder P. Drake
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2017-01-01
Colección:	Journal of Immunology Research
Acceso en línea:	http://dx.doi.org/10.1155/2017/3642832
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