In Vitro Activity of Novel Antifungal Olorofim against Filamentous Fungi and Comparison to Eight Other Antifungal Agents

Olorofim is a novel antifungal drug that belongs to the orotomide drug class which inhibits fungal dihydroorotate dehydrogenase (DHODH), thus halting pyrimidine biosynthesis and ultimately DNA synthesis, cell growth and division. It is being developed at a time when many invasive fungal infections e...

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Egile Nagusiak:	Ourania Georgacopoulos, Natalie S. Nunnally, Eric M. Ransom, Derek Law, Mike Birch, Shawn R. Lockhart, Elizabeth L. Berkow
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2021-05-01
Saila:	Journal of Fungi
Gaiak:	olorofim F901318 filamentous fungi antifungal agents <i>Aspergillus fumigatus</i> <i>Fusarium</i> spp.
Sarrera elektronikoa:	https://www.mdpi.com/2309-608X/7/5/378
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