A bypass flow model to study endothelial cell mechanotransduction across diverse flow environments

Disturbed flow is one of the pathological initiators of endothelial dysfunction in intimal hyperplasia (IH) which is commonly seen in vascular bypass grafts, and arteriovenous fistulas. Various in vitro disease models have been designed to simulate the hemodynamic conditions found in the vasculature...

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Detalhes bibliográficos

Principais autores:	Zhuotao Xiao, Rudmer J. Postma, Anton Jan van Zonneveld, Bernard M. van den Berg, Wendy M.P.J. Sol, Nicholas A. White, Huybert J.F. van de Stadt, Asad Mirza, Jun Wen, Roel Bijkerk, Joris I. Rotmans
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Materials Today Bio
Assuntos:	Disturbed flow In vitro model Vascular bifurcation Computational fluid dynamics High-content screening
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2590006424001807
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