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Regioselective Pd-Catalyzed Hydroalkynylation of Allenyl-Containing α-Amino Acid Derivatives with Terminal Alkynes

An efficient access to the novel representatives of α,α-disubstituted α-amino acids with 1,3-enyne unit located at their side chain has been elaborated. The method is based on Pd(II)-catalyzed hydroalkynylation of α-allenyl-α-dimethylamino esters with terminal acetylenes. The developed strategy is t...

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Principais autores: Alexandra S. Bubnova, Daria V. Vorobyeva, Ivan A. Godovikov, Anna N. Philippova, Pavel S. Gribanov, Evgenia P. Antoshkina, Sergey N. Osipov
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2025-09-01
סדרה:Molecules
נושאים:
1,3-enynes
allenes
alkynes
hydroalkynylation
catalysis
גישה מקוונת:https://www.mdpi.com/1420-3049/30/17/3623
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