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Mechanisms underlying immunodynamics of layered defenses elicited by mRNA vaccination in children

Abstract Background Defining the ever-evolving correlates of protection against symptomatic infection is critical in light of the widespread deployment of mRNA vaccines in children. Since immune maturation and exposure histories differ between children and adults, immune kinetics and correlates of p...

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Autori principali: Yiyu Liao, Hoong Kai Chua, Boon Kiat Law, Yuqian Wang, Franciszek Polak, Allyson N. X. Choi, Carina J. X. Tay, Hui’En Li, Lynette P. Shek, Elizabeth Huiwen Tham, Youjia Zhong, Keisuke Ejima
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-04-01
Serie:BMC Medicine
Soggetti:
mRNA vaccine
Children
Biomarkers
Antibodies
B cell
T cell
Accesso online:https://doi.org/10.1186/s12916-026-04852-6
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