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Brozopine Inhibits 15-LOX-2 Metabolism Pathway After Transient Focal Cerebral Ischemia in Rats and OGD/R-Induced Hypoxia Injury in PC12 Cells

The goal of this study was to elucidate the mechanisms of protection of Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (trade name: Brozopine, BZP) against cerebral ischemia in vivo and in vitro. To explore the protective effect of BZP on focal cerebral ischemia-reperfusion injury, we evaluated the...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan Gao, Xinyu Cao, Xiaojiao Zhang, Yangjun Wang, He Huang, Yonggang Meng, Junbiao Chang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020-02-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Online Erişim:https://www.frontiersin.org/article/10.3389/fphar.2020.00099/full
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