Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI‐dimer—An interaction that may modulate fibrin crosslinking

Abstract Background In the fibrin‐forming process, thrombin cleaves fibrinogen to fibrin, which form fibrils and then fibers, producing a gel‐like clot. Thrombin also activates coagulation factor XIII (FXIII), which crosslinks fibrin γ‐chains and α‐chains, stabilizing the clot. Many proteins bind to...

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Autors principals:	Masaaki Moroi, Isuru Induruwa, Richard W. Farndale, Stephanie M. Jung
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-03-01
Col·lecció:	Research and Practice in Thrombosis and Haemostasis
Matèries:	crosslinking factor XIII fibrin fibrin clot GPVI GPVI‐dimer
Accés en línia:	https://doi.org/10.1002/rth2.12697
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