Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4

In the present study, we aim to identify a potential drug candidate that targets the Monocarboxylate Transporter-4 (MCT-4) protein. Syrosingopine (SRY) is a well-established inhibitor of lactate transport through MCT-4. We screened 2,11,192 potential leads through ZINC database, which were atleast 5...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Asma Khatoon Zaidi, Anurag Kumar, Rohit Kumar, Jyoti Singh, Sneha Yadav, Archana Bharti Sonkar, Dharmendra Kumar, Neeraj Kumar Shrivastava, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-06-01
سلاسل:	Toxicology Reports
الموضوعات:	Monocarboxylate Transporter-4 Syrosingopine Brucine Breast cancer Lactate
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2214750025000204
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!