Time to benefit estimation in multicenter studies using flexible hazard shared frailty models
Abstract Background Time to benefit (TTB) has emerged as a clinically interpretable estimand for characterizing when treatment effects become meaningful over time. Unlike conventional survival summaries, TTB is implicitly defined through marginal differences in survival probabilities and is therefor...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2026-03-01
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| Collection: | BMC Medical Research Methodology |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1186/s12874-026-02816-1 |
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