Letrozole, abemaciclib and metformin in endometrial cancer: a non-randomized phase 2 trial
Abstract Based on preclinical studies showing synergism with simultaneous inhibition of the estrogen receptor (ER), CDK4/6 and PI3K pathways and based on window of opportunity studies showing that metformin suppresses PI3K/mTOR signaling in endometrial cancer (EC), we conduct a non-randomized phase...
Na minha lista:
| Principais autores: | , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-12-01
|
| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-025-67087-8 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|
